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Alimta®


Producer: Eli Lilly

contains

Alimta® is a cell-inducing agent (antimetabolite).

Active substances

pemetrexed


Application

Alimta® is used to treat certain forms of prolonged and mesothelioma. Only used in hospitals.


Dosage

Available as powder for solution for infusion, which is administered in a vein after reconstitution.

  • The treatment is individual and tailored according to the effect, partly by the degree and extent of adverse reactions.

possible side effects

Very common (over 10%)

Reduced appetite, Fatigue

Diarrhea, Constipation, Nausea, Otitis, Vomiting

Influence of bone marrow production of blood cells

Skin rash, Hair loss

Increased creatinine in the blood

Common (1-10%)

Fever

Digestive Disorders, Liver Impact, Abdominal Disorders, Taste Disorders

dehydration

Nervous inflammation, eg on the arms and legs

Severe skin reaction, skin rash, hives

Allergic reactions, Infections

Impact of the kidneys

conjunctivitis


Should not be used

Should not be used

  • by very poorly functioning kidneys
  • if you have recently been vaccinated with mod yellow fever.

Pregnancy

Use only under certain conditions.
  • There is limited experience with the use of Alimta┬« in pregnant women. Should only be used in special cases after consultation with the specialist.

breastfeeding

Do not use.

Traffic

No warning.

Blood donor

Do not drop. Donor must be declared by the donor village.

effect

  • Works by inhibiting the conversion of folic acid. The agent thus interferes with the metabolism of the cell, e.g. by inhibiting the build-up of DNA (the cell's genetic code) that is crucial to the cell's function and survival.
  • The half life in the blood (T?) is approximately 3.5 hours

Pharmaceutical forms

Powder for concentrate for solution for infusion. 1 vial contains 100 mg or 500 mg pemetrexed (as disodium salt).


Special warnings

  • Alimta┬« should be used with caution in poorly functioning kidneys and bone marrow.
  • Vaccination with live vaccine should be avoided.

Using other medicines

It is important to inform your doctor about all the medicines you are taking.
  • High doses of NSAIDs (anti-rheumatic and painful agents) increase the effect and enhance the side effects of Alimta┬«. In particular, long-term NSAIDs should be avoided from 2-5 days before to 2 days after treatment with Alimta┬«.
  • Caution should be exercised when co-administered with penicillin or probenecid (antidiabetic agent).

Grants, delivery, packages and prices

subsidiesextraditionDispensing form and strengthPackingPrice in kr.
May only be delivered to hospitals. Delivered according to the provisions for drugs in delivery group Apowder for concentrate for solution for infusion, dissolve 100 mg1 htgl.3.108,95
May only be delivered to hospitals. Delivered according to the provisions for drugs in delivery group Apowder for concentrate for solution for infusion, opl. 500 mg1 htgl.12.896,80




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