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AmBisome®


Producer: Gilead Sciences

contains

AmBisome® is a fungicide.

Active substances

Amphotericin B (liposomal)


Application

AmBisome® is used to treat:

  • Serious widespread infections with fungi that may be affected by amphotericin B.

Only used in hospitals.


Dosage

Available as powder for solution for infusion, which is administered in a vein after reconstitution.

The dose is individual and depends on the nature and severity of the disease.


possible side effects

Very common (over 10%)

Fever, Chills

Nausea, Vomiting

Too little potassium in the blood

Common (1-10%)

Diarrhea, Liver Impact, Abdominal Disorders

Relaxation of the muscles of the vessels, fast pulse, low blood pressure, shortness of breath

Chest pain, Too little calcium in the blood, Too low sodium in the blood, Increased blood sugar

Back pain

Headache

Hududsl?t, R?dme

Increased creatinine in the blood, Increased urea in the blood

Uncommon (0.1-1%)

Muscle contractions in the airways

Increased tendency to bleeding due to decrease in platelets

Seizures

Anaphylactic shock - an acute severe allergic condition

There have been rare cases of cardiac arrest, allergic swelling of the face, oral cavity and larynx, kidney damage and muscle tissue degradation.



Pregnancy

Should not be used due to lack of knowledge. This text differs from the company's approved product information (product summary).Do not be used due to lack of knowledge. This text differs from the company's approved product information (product summary).

breastfeeding

Should not be used due to lack of knowledge.

Traffic

No warning.

Blood donor

Do not drop. 8 weeks quarantine after end of treatment.

effect

  • Works by destroying the cell walls of the fungi so that they go to the ground.
  • The half life in the blood (T?) is approximately 7 hours.

Pharmaceutical forms

Powder for solution for infusion. 1 vial contains 50 mg amphotericin B (liposomal).


Special warnings

AmBisome® should be used with caution when:

  • Badly functioning kidneys.
  • The function of the kidneys, the function of the liver and the blood's content of salts are regularly monitored during treatment with AmBisome┬«.

Using other medicines

It is important to inform your doctor about all the medicines you are taking.
  • AmBisome┬« increases the effect of digoxin (cardiac agent) and increases the risk of digoxin poisoning.
  • The risk of side effects is increased by concurrent use of:
    • adrenal gland hormones (tablets or injections)
    • aminoglycosides (antibiotics)
    • cisplatin (cancer)
    • ciclosporin (agent of organ transplant).

Grants, delivery, packages and prices

subsidiesextraditionDispensing form and strengthPackingPrice in kr.
May only be delivered once after the same recipe, unless the delivery takes place in several smaller portions at a timepowder for solution for infusion, opl.50 mg10 pcs.24.814,60
May only be delivered once after the same recipe, unless the delivery takes place in several smaller portions at a timepowder for solution for infusion, opl.50 mgAbacus10 pcs.24.850,00
May only be delivered once after the same recipe, unless the delivery takes place in several smaller portions at a timepowder for solution for infusion, opl.50 mgOrifarm10 pcs.24.814,60




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