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Amiodarone "Orion"


Producer: Orion Pharma

contains

Amiodarone "Orion" is a means of cardiac arrhythmia.

Active substances

amiodarone


Application

Amiodarone "Orion" is used for the prevention and treatment of life-threatening cardiac arrhythmias where other treatment has been ineffective.

Only used in hospitals.


Dosage

Available as a concentrate for injection and infusion, injected into a vein after dilution.

  • The dose is individual. Usually 5 mg per kg body weight.
  • This is usually continued with tablet treatment.

possible side effects

Very common (over 10%)

Indigestion, Constipation, Taste Disorders

muscle weakness

Hypersensitivity to sunlight

Particle deposits in the eye, Dry eyes

Common (1-10%)

Reaction at the injection site

Badly functioning liver, jaundice, liver effect

Pneumonia in the lungs, Irritation in the lungs, Slow heart rate, Low blood pressure, Pneumonia

Increased metabolism, Reduced metabolism

Headache, Nightmare, Shaking, Dizziness, Sleep Disorders

Eczema, Changed color in the skin

Uncommon (0.1-1%)

Disturbances in the pulse between the central and central chambers of the heart, cardiac arrhythmias, cardiac arrest

muscle Disease

neuritis

Very rare (less than 0.01%)

Hepatitis, cirrhosis

Carcinoma, Muscular Complications in the Pneumonia, Breathing Disorders in Newborns

Blood deficiency, increased tendency to bleeding due to decrease in platelets

Special kidney disease - Schwartz-Bartter syndrome

Difficulty in controlling arms and legs, Increased pressure in the brain

Severe skin reaction, hair loss

Impotence

Inflammation of the optic nerve, blindness

Unknown

Inflammation of the pancreas

Heart Bank, Removal of blood, shortness of breath

Increased risk of infection due to lack of white blood cells

Delirium - a state of confusion and influence on visual and hearing impairment, hallucinations, Parkinsonism

Severe skin reaction where skin is damaged, Serious drug reaction with internal organs, Skin rash with bladder formation

Allergic swelling of the face as well as the oral cavity and larynx, anaphylactic shock - an acute severe allergic condition


Should not be used

The agent should not be used for:

  • certain types of irregular heart function
  • thyroid diseases
  • hypersensitivity to iodine.

Pregnancy

Use only under certain conditions.

There is limited experience with the use of Amiodarone "Orion" in pregnant women. The drug may affect the fetus thyroid gland. Should be used only in agreement with the specialist.


breastfeeding

Do not use this text. This text differs from the company's approved product information (product summary).

Traffic

No warning.

Blood donor

Do not drop. Donor must be declared by the donor village.

effect

  • Works by inhibiting the electrical impulses in the heart muscle so that the heart's rhythm is normalized.
  • The effect may last for weeks after the end of treatment as the substance is excreted very slowly.

Pharmaceutical forms

Concentrate for solution for injection and infusion. 1 ml contains 50 mg of amiodarone hydrochloride.


Special warnings

  • Grapefruit juice should be avoided as it reduces the effect of the drug.
  • During treatment you should have regularly checked your thyroid gland, lung function and liver function.
  • If you get blurred or impaired vision, consult your doctor.

Using other medicines

It is important to inform your doctor about all the medicines you are taking.
  • Amiodarone "Orion" must not be used in combination with antipsychotics (haloperidol, sertindole), tricyclic antidepressants, terfenadine (antihistamine), cholesterol lowering agents (atorvastatin and simvastatin) and quinine (against drug cramps).
  • Caution in co-administration with drugs that affect, eg sotalol (beta-blockers), loratadine (antihistamine) and certain anti-psychotic agents.
  • Concomitant treatment with anti-inflammatory agents (daclatasvir, ledipasvir and sofosbuvir) increases the risk of slow pulse. In case of pronounced symptoms of slow pulse, eg dizziness and fainting, consult your doctor.
  • Amiodarone "Orion" increases the effect of digoxin (cardiac agent) and warfarin (blood thinning).
  • There is a risk of bleeding when co-administered with dabigatran (blood thinning).
  • Amiodarone "Orion" may increase the effect of certain anti-arrhythmias (flecainid) agents, organ transplants (ciclosporin and tacrolimus), metoprolol (beta-blockers) and phenytoin (epilepsy).
  • Rifampicin (anti-tuberculosis) and herbal remedies can reduce the effect of Amiodarone "Orion".

Grants, delivery, packages and prices

subsidiesextraditionDispensing form and strengthPackingPrice in kr.
May only be delivered once after the same recipe, unless the delivery takes place in several smaller portions at a timeconcentrate for solution for injection and infusion, solution 50 mg / ml10 x 3 ml125,80




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