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Methotrexate "Sandoz"


Producer: Sandoz

contains

Methotrexate "Sandoz" is a rheumatoid and anticorrosive agent (antimetabolite). Note: There have been serious errors in handling this medicine. For rheumatoid arthritis and psoriasis, the dose should only be given once a week.

Active substances

methotrexate


Application

Methotrexate "Sandoz" is used to treat

  • leddegigtogpsoriasis (low dose)
  • certain types of cancer, including breast cancer, bladder cancer leukemia (cancer of the blood).

Dosage

Available as tablets.

The dose depends on the nature and severity of the disease.

rheumatoid arthritis

  • Usually 2-10 tablets (5-25 mg) 1 time a week.

psoriasis

  • Usually 2-10 tablets (5-25 mg) 1 time a week.

cancer

  • The treatment is individual and tailored according to the effect, partly by the degree and extent of adverse reactions.

Note

  • The joint can be used to facilitate intake. It can not be guaranteed that half a tablet contains half dose.

possible side effects

The incidence and severity of side effects depend on the size of the doses used.

Very common (over 10%)

Reduced appetite

Increased gall dye, nausea, liver reaction, abdominal pain, vomiting

Common (1-10%)

Fever, Chills, Fatigue

Diarrhea, mouth inflammation, mouth ulcers

Blood deficiency, bleeding, increased risk of infection due to lack of white blood cells, increased tendency for bleeding due to decrease in platelets

Headache, change in skin sensation

Inflammation of the mucous membranes

infections

Uncommon (0.1-1%)

Hepatic fibrosis, inflammation of the pancreas, gastrointestinal bleeding, cirrhosis of the liver

Pancreatitis, Pneumonia, Liquids in the lungs, Liquid fluid collection

Blood deficiency and increased risk of infection due to lack of white blood cells, swollen lymph nodes

Bone cramps, joint pain

Depression, Confusion, Stomatitis, Cramps, Paralysis, Paralysis in one face and body, Dizziness, Mood swings

Serious skin reaction, Serious skin reaction where skin is damaged, Hair loss

Allergic reactions, anaphylactic shock - an acute severe allergic condition

Reduced sperm count in sperm, renal failure

Rare (0.01-0.1%)

Later cases of cancer

hepatitis

Lung Scar tissue, Blood clots, Low blood pressure, Stains on the X-ray of the lungs, Shortness of breath

Diabetes, Salt Balance Disorder

fracture

Mood swings, Reduced muscle tension, Thoughts and memory problems

Skin inflammation, Sensitivity to sunlight, Skin bleeding and mucous membranes, Wound healing problems

blood poisoning

visual disturbances

Very rare (less than 0.01%)

Suddenly dead

Vomiting of blood

Inflammation of the heart's barrier, fluid accumulation in the heartbone

Blood in the urine

Transient blindness, Tinnitus

Unknown

Bleeding in the lungs

Influence of the nervous system

If the organism is unable to get rid of all the cells that Methotrexate "Sandoz" has broken, so-called tumor light can occur, which can lead to an abnormally high levels of waste in the blood and possibly kidney failure. If side pain occurs or blood is present in the urine, it may be a sign of tumor light and in this case you should seek medical advice.



Pregnancy

Do not use.
  • Psoriasis and rheumatoid arthritis: Women must not become pregnant during treatment, and all patients (both women and men) must use safe contraception during treatment and for at least 3 months thereafter.
  • cancer: Can be used under certain conditions.

breastfeeding

Do not use.

Traffic

No warning.

Blood donor

Do not drop. Donor must be declared by the donor village.

effect

  • Works by inhibiting the conversion of folic acid. The agent thus interferes with the metabolism of the cell, e.g. by inhibiting the build-up of DNA (the cell's genetic code) that is crucial to the cell's function and survival.
  • The half life in the blood (T?) is 3-10 hours.

Pharmaceutical forms

tablets. 1 tablet contains 2.5 mg methotrexate (as disodium salt).


Special warnings

The drug should be used with caution at

  • age over 70 years
  • diabetes
  • overweight
  • certain lung diseases
  • poor functioning bone marrow.

Note: There have been serious errors in handling this medicine. In rheumatoid arthritis and psoriasis, the dose should only be given 1 time a week. There have been examples of overdose causing death. Read more about mistakes with Methotrexat "Sandoz" at pro. under "Typical Serious Errors."


Using other medicines

It is important to inform your doctor about all the medicines you are taking.
  • Acetylsalicylic acid (anti-rheumatic and painful) antidiabetic agents (phenylbutazone and probenecid), omeprazole (antidiabetic agent) and trimethoprim (antibiotic) may increase the effect of Methotrexate "Sandoz".
  • Liver function should be monitored when co-administered with leflunomide (anti-rheumatoid arthritis), azathioprine (anti-cancer and organ transplant), sulfasalazine (rheumatoid arthritis), isotretinoin (anti-inflammatory) and acitretin (anti-psoriasis).

Grants, delivery, packages and prices

subsidiesextraditionDispensing form and strengthPackingPrice in kr.

Methotrexate

May only be delivered once after the same recipe, unless the delivery takes place in several smaller portions at a timetablets 2.5 mg100 pieces. (Blister)183,95


substitution

2.5 mg tablets

EmthexateTEVA Methotrexate

Methotrexate "2care4" Parallel Methotrexate

Methotrexate "Orifarm" Parallel Import Methotrexate


Methotrexate

FAQ - 💬

❓ What is methotrexate used to treat?

👉 Methotrexate calms your immune system, to help stop it attacking your body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis, thickened skin in psoriasis or damage to your bowel in Crohn's disease. Methotrexate is not a painkiller.

❓ Is methotrexate a strong medication?

👉 Methotrexate is a strong medication. The dosage and how often you take this medication are based on your medical condition and response to treatment. There are many different dosing schedules for this medication (especially for cancer treatment).

❓ Why is methotrexate taken only once a week?

👉 Abstract. Methotrexate (MTX) treatment for psoriasis is most often administered weekly, because the drug has been considered more hepatotoxic when taken daily. However, some patients may tolerate smaller, more frequent doses better.

❓ What are the serious side effects of methotrexate?

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  • Black, tarry stools.
  • blood in the urine or stools.
  • bloody vomit.
  • increased heartbeat.
  • itching, rash, reddening of the skin.
  • sores in the mouth or lips.
  • stomach pain.
  • swelling of the eyelids, face, lips, hands, feet, or lower legs.

❓ What are the signs that methotrexate is working?

❓ How long can you be on methotrexate?

❓ What can you not do while on methotrexate?

❓ Why can you not touch methotrexate?

❓ How long do you stay on methotrexate?

❓ When should I take methotrexate morning or night?

❓ Do you take methotrexate for life?


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