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PuregonĀ®


Producer: MSD

contains

PuregonĀ® is a medicine for infertility. Follicle-stimulating hormone (FSH).

Active substances

Follitropin beta


Application

  • PuregonĀ® is used in certain forms of impotence, often in connection with artificial fertilization.
  • Can also be used for men with poor sperm quality due to lack of overall sex hormone FSH.
  • May only be obtained from hospital or specialist.

Dosage

Available as a syringe under the skin or in a muscle.

  • The dose is determined individually by the doctor
  • You take your injections yourself after instruction.

Note: Injection vial in cartridge is intended for use in special pen.


possible side effects

Common (1-10%)

Reactions and discomfort at the injection site

Abdominal pain, bloating

Development of breasts in men

pelvic pain

Headache

Acne (in men), Hududsl?t

Overstimulation of the ovaries

Uncommon (0.1-1%)

Bleeding from the uterus, bleeding from the vagina, ovarian cysts, ovarian ovary, enlarged ovaries, enlarged uterus


Should not be used

Puregon should not be used in:

  • tumor in the pituitary gland
  • breast cancer or uterine cancer
  • benign nodules in the womb
  • ovarian cysts without having PCOs
  • malformations in the genitals
  • bleeding from the vagina without known cause.

Pregnancy

Not applicable.

breastfeeding

Not applicable.

Traffic

No warning.

Blood donor

Do not drop. 7-day quarantine.

effect

  • Works by stimulating the maturation of the egg.
  • In artificial fertilization, the mature eggs are taken for artificial fertilization. The technique used allows fertilization of several eggs.
  • The half life in the blood (T?) is approximately 40 hours.

Pharmaceutical forms

Solution for injection in cartridge. 1 cartridge contains 300 IU, 600 IU or 900 IU follitropin beta.

Special warnings

  • In patients with polycystic ovary syndrome there is a risk that treatment with PuregonĀ® may cause ovarian hyperstimulation. It appears in abdominal pain, bloating, nausea, possibly. vomiting and weight gain.
  • Certain antibiotics (streptomycin and / or neomycin) may also cause hypersensitivity reactions.


Grants, delivery, packages and prices

subsidiesextraditionDispensing form and strengthPackingPrice in kr.

PuregonĀ®

solution for injection.300 IU1 piece (0.36 ml) (Orifarm)988,00

PuregonĀ®

solution for injection.300 IU1 piece. (0.36 ml)925,95

PuregonĀ®

solution for injection.300 IU1 piece (0.36 ml) (Haemato)939,50

PuregonĀ®

solution for injection.300 IU1 piece. (0.36 ml) (Paranova)989,60

PuregonĀ®

solution for injection.300 IU1 piece. (0.36 ml) (2care4)1.028,05

PuregonĀ®

solution for injection.300 IU1 piece. (0.36 ml) (Abacus)919,00

PuregonĀ®

solution for injection, opl. 600 IU1 piece. (0.72 ml) (Orifarm)1.748,00

PuregonĀ®

solution for injection, opl. 600 IU1 piece. (0.72 ml) (Paranova)1.848,70

PuregonĀ®

solution for injection, opl. 600 IU1 piece. (0.72 ml) (Abacus)1.710,00

PuregonĀ®

solution for injection, opl. 600 IU1 piece. (0.72 ml) (EuroPharmaDK1.732,15

PuregonĀ®

solution for injection, opl. 600 IU1 piece. (0.72 ml)1.677,95

PuregonĀ®

solution for injection, opl.900 IU1 pc (1.08 ml) (Europharma)2.836,50

PuregonĀ®

solution for injection, opl.900 IU1 piece. (1.08 ml) (2care4)2.779,00

PuregonĀ®

solution for injection, opl.900 IU1 pc (1.08 ml) (Abacus)2.719,00

PuregonĀ®

solution for injection, opl.900 IU1 piece. (1.08 ml)2.725,35



PuregonĀ®

FAQ - 💬

❓ What is Puregon used for?

👉 Puregon can be used to cause ovulation in women who have not responded to treatment with clomiphene citrate. Puregon can be used to bring about the development of multiple follicles in women undergoing assisted reproduction technologies (ART) such as in vitro fertilisation (IVF).

❓ Is Puregon better than Gonal-F?

👉 Conclusions: Gonal-F (Follitropin-a) is associated with a potential stimulatory effect on ovaries. Puregon (Follitropin-b) was associated with a lower clinical pregnancy rate (PR). E2 level 5-7 days after stimulation can be used as an indicator of the success of IVF.

❓ How quickly does Puregon work?

👉 In men, the usual dose is 150 IU given 3 times a week or 225 IU twice a week. Treatment is usually given for at least 3 to 4 months. It is usually given along with another medication, hCG. Response to this medication for men is determined by analysis of semen after 4 to 6 months of treatment.

❓ Does Puregon cause acne?

👉 In males, Puregon can cause some side effects as well, including: Injection site reactions: redness, bruising, swelling, pain, itching. Headache. Acne and skin rashes.

❓ How quickly do follicles grow?

👉 As follicles grow ~1.7 mm per day, follicle sizes presented in this study would be expected to be ~3ā€“4 mm smaller than comparable studies assessing follicular sizes on the day of oocyte retrieval (1, 24).

❓ Does Puregon stop ovulation?

👉 Women: In women who do not ovulate and do not respond to treatment with clomid, Puregon can be used to cause ovulation. In women undergoing assisted reproduction techniques, including in vitro fertilisation (IVF) and other methods, Puregon can bring about the development of multiple follicles.

❓ Does Gonal F improve egg quality?

👉 Gonal F stimulates the ovary to produce healthy eggs. It is most commonly used in conjunction with fertility treatments, especially IVF, to encourage women's ovaries to produce multiple eggs in one cycle.

❓ How long do you take Gonal F for IVF?

👉 If everything has gone to plan, the patient then starts daily injections of stimulation drugs, which are designed to stimulate follicle growth (e.g. Gonal-F/ Menopur). You will take these injections for 12 days, and may continue with the Buserelin too during this period.

❓ What should I avoid during IVF?

👉 Avoid red meat, sugar, refined grains, and other highly processed foods.

❓ What is the best size of follicle to conceive?

👉 Pregnancy was recorded as clinical pregnancy with fetal heart activity seen at 6- to 7-week transvaginal ultrasound. For both CC and letrozole, higher pregnancy rates were achieved when the leading follicles were in the 23 to 28 mm range.

❓ What are the side effects of puregon?

👉 Side Effects of Puregon

  • pain in your lower stomach area.
  • nausea.
  • vomiting.
  • weight gain.
  • diarrhea.
  • decreased urine output.
  • trouble breathing.

❓ How does Puregon work?

👉 How does Puregon work? The active substance in Puregon, follitropin beta, is a copy of the natural hormone follicle stimulating hormone (FSH). In the body, FSH regulates the reproductive function: in women, it stimulates the production of eggs, and in men, it stimulates the production of sperm by the testicles.

❓ Is Puregon prescribed in the US?

👉 Puregon is usually prescribed in Europe. In the US, you may be more likely to be prescribed Follistim or Gonal-F ā€” in general, gonadotropins all do the same thing, but some are synthetic (Puregon is one of them) and some (like Bravelle) are made from natural hormones (derived from menopausal womenā€™s urine ā€” donā€™t worry; itā€™s highly purified!)

❓ How effective is Puregon for fertility?

👉 Puregonā€™s use in women undergoing fertility treatment has been studied in 981 patients. The number of eggs recovered and the ongoing pregnancy rate were the main measures of effectiveness. Puregon was studied in 172 anovulatory women, measuring how many cycles of treatment were needed for these women to ovulate.

❓ What are the indications of Puregon?

👉 Puregon 1 Therapeutic Indication. Deficient spermatogenesis due to hypogonadotrophic hypogonadism. 2 Puregon is a powder and solvent to be made up into a solution for injection. 3 Puregon is administered to stimulate the ovaries to produce more... 4 Treatment with Puregon should be carried out by...


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