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Ropinirol "Orion"


Producer: Orion Pharma

contains

Ropinirol "Orion" is a medicine for Parkinson's disease.

Active substances

ropinirole


Application

Ropinirol "Orion" is used for Parkinson's disease. The drug may be used alone or in combination with levodopa (another anti-Parkinson's disease).


Dosage

Available as prolonged-release tablets.

  • Adults. The starting dose. Usually 2 mg once a day for the first week. Thereafter, the dose is increased to 4 mg once a day for the second week.
  • Later, the dose may be increased by 2 mg a week to a dose of 8 mg once a day, but doses up to 24 mg may be necessary.
  • Patients in hemodialysis. The recommended maximum dose of prolonged-release tablets is 18 mg a day in patients with regular hemodialysis. Note:
    • The prolonged-release tablets should be swallowed whole.
    • The prolonged release tablets must does not chewed or crushed.
    • The dose should be taken at the same time each day.

possible side effects

Side effects are primarily related to the treatment of parkinsonism and are seen less frequently in treatment of Restless Legs Syndrome due to the lower dosage. Volunteering movements are most commonly seen when used in combination with levodopa, but may be reduced when decreasing dose of levodopa.

Very common (over 10%)

Nausea

Fainting, sleepiness, involuntary moving movements

Common (1-10%)

Fatigue

Constipation, Heartburn, Abdominal pain, Vomiting

Blood pressure drop when you get up, low blood pressure, fluid accumulation in eg arms and legs

Confusion, worsening and recurrent symptoms *, hallucinations, dizziness

Uncommon (0.1-1%)

Delirium - a state of confusion and influence on visual and hearing impairments, sudden sleep apnea, psychosis

Unknown

Abstinence associated with retardation, Aggressivity **, Dopamine dependence ****, Malignant neuroleptic syndrome - Serious condition with, inter alia, fever and awareness raising ***, game science **

Hypersensitivity (including urticaria, allergic swelling of the face, oral cavity and larynx, skin rash, skin itching)

* Worsening of Restless Legs Syndrome, where symptoms begin either earlier in the day than expected, with increased intensity or with proliferation to body parts that were not previously affected. Symptoms can also return early in the morning. In such cases, the doctor may reduce the dose or stop treatment.

** Patients with Parkinson's disease treated with agents that increase dopamine's effect in the brain (dopamine agonists) have shown signs of play and increased sex drive, especially at high doses. These side effects disappear when you reduce the dose or stop treatment with the drug.

*** Symptoms suggesting malignant neuroleptic syndrome have been reported. The reason has been that some patients abruptly stopped treatment rather than slowly stepping out of it.

**** Parkinson's medicine may be addictive to some people, and there may be a strong urge to take more medicine than prescribed by the doctor - even if the symptoms of Parkinson's disease over time do not worsen. This addiction, however, appears relatively rarely.


Should not be used

In very poorly functioning kidneys and in poorly functioning liver, the product should not be used.


Pregnancy

Should not be used due to lack of knowledge. This text differs from the company's approved product information (product summary).Do not be used due to lack of knowledge. This text differs from the company's approved product information (product summary).

breastfeeding

Should not be used due to lack of knowledge.

Traffic

Caution is advised in driving and machine operation.

Blood donor

Do not drop. Donor must be declared by the donor village.

effect

  • Effects on affecting the balance between different signal substances in the brain, including dopamine and acetylcholine.
  • Ropinirol "Orion" increases the effect of dopamine, reducing muscle rigidity and shaking.
  • In patients in the terminal stage of renal disease and with regular hemodialysis, the drug secretion is reduced (by approximately 30%) and therefore the dose to patients should be lower.

Pharmaceutical forms

Prolonged-release tablet. 1 prolonged-release tablet contains 2 mg or 8 mg ropinirole (as hydrochloride).


Special warnings

  • Sleep cases without prior notice may occur during the day.
  • Tell your doctor if you or your family notices that you are developing a behavior that is unusual for you, such as habit and impulse actions that may include sick play, excessive eating or spending money, abnormal sex drive, or increased sexual thoughts and feelings.
  • In addition, there is a risk of hallucinations, especially in the elderly.
  • Depression with dopamine agonists should take place slowly. Rapid withdrawal may cause symptoms such as anxiety, depression, fatigue, sweating and pain that may be difficult. It may be necessary to increase the dose of Ropinirol "Orion" temporarily if symptoms persist.

Using other medicines

It is important to inform your doctor about all the medicines you are taking.
  • Oestrogens (hormones) may increase the effect of Ropinirol "Orion".
  • Certain antipsychotic drugs and metoclopramide (anti-nausea) may reduce the effect of Ropinirol "Orion".
  • Ropinirol "Orion" may increase the effect of blood thinning agents (vitamin K antagonists), so the dose of these may occur. must be reduced.
  • Smoking may reduce the effect of Ropinirol "Orion". Dose adjustment may be required if you suddenly stop or start smoking during treatment with Ropinirol "Orion".

Grants, delivery, packages and prices

subsidiesextraditionDispensing form and strengthPackingPrice in kr.

Ropinirol

May only be delivered once after the same prescription unless the recipient has stated on the prescription, how many times and with what time intervals additional extradition must take placeprolonged release tablets 2 mg84 pcs. (Blister)286,35

Ropinirol

May only be delivered once after the same prescription unless the recipient has stated on the prescription, how many times and with what time intervals additional extradition must take placeprolonged release tablets8 mg84 pcs. (Blister)317,55


dyes

Iron oxides and iron hydroxides (E172)

Titanium dioxide (E171)


substitution

prolonged release tablets 2 mg

Ropinirol "KRKA" KRKA Ropinirol

RopinostadSTADA Nordic Ropinirol

prolonged release tablets 8 mg

Ropinirol "KRKA" KRKA Ropinirol

RopinostadSTADA Nordic Ropinirol



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