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Sertralin "Orion"


Producer: Orion Pharma

contains

Sertralin "Orion" is a means of depression. SSRI.

Active substances

sertraline


Application

  • Sertraline "Orion" for the treatment of depression.
  • The drug is also used for fear of intercourse with others (social phobia), panic disorder, stress after accidents or the like. violent events (post-traumatic stress condition (PTSD)) and obsessive-compulsive condition (OCD)).

Dosage

Available as tablets.

Depression Adults. Usually 50 mg once a day. After one week, the dose can be increased by 50 mg at a time with at least 1 week intervals. The highest daily dose is 200 mg.

Panic Disorders, Social Phobia and Post-Traumatic Stress Disorder (PTSD) The starting dose. 25 mg once a day. The dose may be increased to 50 mg a day after one week and then at 50 mg at a time with at least 1 week intervals. The highest daily dose is 200 mg.

Obsessive Compulsive Condition (OCD)

  • Adults and children over 13 years old. The starting dose. Usually 50 mg once a day. After one week, the dose can be increased by 50 mg at a time with at least 1 week intervals. The highest daily dose is 200 mg.
  • Children 6-13 years. The starting dose. Usually 25 mg once a day. After 1 week, the dose may be increased to 50 mg once a day and then at 50 mg at a time with at least 1 week intervals. The highest daily dose is 200 mg.

possible side effects

Many of the side effects usually occur only at the beginning of treatment.

Very common (over 10%)

Fatigue

Diarrhea, Nausea, Dry mouth

Drowsiness, Headache, Dizziness, Insomnia

Common (1-10%)

Fever, Powerlessness, Reduced or Increased Appetite, Utilpashed, Weight Loss, Increased Risk of Accident

Indigestion, constipation, intestinal gut, abdominal pain, vomiting, taste disorder

Hepatitis, hay fever

Hot flushes

Joint pain, Muscle pain, Back pain, Pain in the chest

Anxiety, Movement Disorders, Depression, Gaben, Concentration Disorder, Nightmare, Nervousness, Asthma, Uncommon, Restlessness or Restlessness to Your Own Person / Own Look or Part of One's Body, Change in Sensory Sensitivity, Increased Muscle Tension

Hududsl?t, Increased sweating

Respiratory Infection

Menstrual Disorders, Reduced Sexual Illness, Travel Issues

Vision disturbances, tinnitus

Uncommon (0.1-1%)

Bleeding from the gastrointestinal tract, Teeth in the teeth, Disease of the tongue

Elevated blood pressure, Cardiac arrest, Muscle contractions in the trachea, Fluid accumulation in, for example, arms and legs, Spiritlessness

Tendency to bleeding

Reduced drug stiffening

muscle weakness

Aggressiveness, Fainting, Hallucinations, Hallucinations, Memory Disorders, Coordination Disorders, Cramps, Migraines, Impaired Sensation, Mood, Psychosis, Suicidal thoughts or behaviors, Dullness, Speech disorders, Disturbances of thought

Skin inflammation, hair loss, skin bleedings and mucous membranes, fluid retention on the face

Allergic reactions (seasonal), Hypersensitivity

Blood in the urine, Bleeding from the vagina, Acute nodules, Missing urination, Sexual disturbances, involuntary urination, difficulty in urinating

Swelling around the eyes, ear pain

Rare (0.01-0.1%)

Dependence of the agent

Inflammation of the pancreas, Inflammation of the lower intestine, Brok, Liver effect (including inflammation of the liver, jaundice and poor functioning of the liver), Ectitis

Blood thrombosis in the heart, Respiratory distress, Heartbone *, Slow heart rate, Local anemia in eg arms and legs, Pulmonary disease, Reduced breathing, Impact of eczema (including prolonged QT interval *), Complications of blood vessels in the brain, Complications of the musculoskeletal

Inflammation of the lymph nodes, increased risk of infection due to lack of white blood cells, increased tendency to bleeding due to decrease in platelets

Diabetes, Too much sodium in the blood, Too much cholesterol in the blood, Increased blood sugar, Low blood sugar, Men's breasts development, Increased amount of hormone prolactin in the blood

Muscle tissue degradation, Increased risk of fractures

Disturbances in the connection between eg identity and memory or sensory sensations and recognition, coma, malignant neuroleptic syndrome - severe condition with inter alia fever and awareness raising, motor disorder, suicidal ideation, serotonin syndrome, involuntary moving movements, increased sensitivity

Serious skin reactions, Inflammation of the hair follicles, Skin rash with bleeding, Hypersensitivity to sunlight

Allergic swelling of the face as well as the oral cavity and larynx, anaphylactic shock - an acute severe allergic condition

Inflammation in and around the vagina, inflammation-like skin reaction on the penis, prolonged painful erection, decreased urinary output

Ocular bleeding, Double vision, Different pupil sizes, Green throat

Unknown

Persistent cramps in the chewing gum

* Prolonged QT interval is a particular type of heart rhythm disorder, which in some cases can lead to sudden death.

  • Serotonin syndrome (inter aliafever, stiffness, shaking, muscle cramps and altered mental state) and malignant neuroleptic syndrome (including muscle rigidity, involuntary movements in the arms and legs, shaking, confusion, speech and swallowing difficulty, high fever, unstable blood pressure) have occurred with SSRI funds. Both conditions may be severe and require quick medical attention. The risk is increased by concomitant use of a variety of other means, including other agents for depression, certain agents for migraines and psychosocial agents.
  • Certain side effects such as fatigue and sleep disturbances may be difficult to distinguish from the disease itself.


Pregnancy

Can be used if necessary.

You have knowledge of several thousand pregnant women who have been treated during the first 3 months of pregnancy without having a fetus injury. However, there may be a small risk that the child may have high blood pressure in the lung cycle with shortness of breath, rapid breathing and bluish skin and lips.

If you are treated late in pregnancy, your child may be affected after birth. In the vast majority of cases, mild symptoms (crying, shaking and difficulty in dying and sleeping) are perceived by themselves. In some rare cases, symptoms may be more severe with convulsions and breathing difficulties.


breastfeeding

Can be used if necessary.

There are only very small amounts of Sertralin "Orion" in breast milk, therefore Sertralin "Orion" may be used. However, always ask your doctor if you are breastfeeding and taking Sertralin "Orion".


Traffic

No warning.

Blood donor

Do not drop. 7-day quarantine.

effect

by increasing the amount of the signal substanceserotoninwhich is important for the pulse transmission in the brain. The regulation of these pulses seems to play some role in the development of depression, but the exact mechanism of action is not known. The full effect of depression can be expected after 3-4 weeks of treatment.

The half life in the blood (T?) is approximately 26 hours.


Pharmaceutical forms

Tablets. 1 tablet (film-coated) contains 50 mg (deletion) or 100 mg of sertraline (as hydrochloride).


Special warnings

  • Possible increased risk of suicidal ideation or suicide behavior at the start of treatment, especially in young people under 25 years of age. In the first weeks of treatment and changes in dose, attention should be paid to indications of possible suicidal ideation or suicide attempts at all - especially in symptoms of anxiety or if there have been cases of suicidal behavior in the past.
  • In children and adolescents under 18 years of age, there is an increased risk of suicidal behavior and aggression. The drug should only be used for children and adolescents under 18 years of age in obsessive compulsive condition (OCD) and the treatment should be carried out by a specialist in child and adolescent psychiatry. For long-term treatment of children, physical and mental development should be monitored regularly. Special attention should also be paid to signs of suicidal behavior.
  • In the treatment of panic attacks, anxiety may be worse at the start of treatment.
  • Vedchizophrenia The psychotic symptoms worsen.
  • For long-term treatment of children, physical and mental development should be monitored regularly.
  • The product should be used with caution when:
    • Green
    • Badly functioning liver (should be avoided by very poorly functioning liver)
    • Epilepsy and impaired convulsion threshold
    • Mani
    • Increased tendency for bleeding
    • Increased risk of decreased sodium content in the blood
    • Simultaneous treatment with Electrostimulation (ECT).
  • If signs of cravings, cramps or worsening of epilepsy occur, treatment should be discontinued.
  • SSRI type antidepressants may reduce bone mass and thus increase the risk of fractures. However, decreased bone mass is also seen in untreated depression.
  • Risk of blood sugar if you suffer from diabetes.
  • The drug should be used with caution if there is an increased risk of developing prolonged QT interval - a particular type of rhythm disturbance in the heart. For example, too little potassium in the blood, slow heart rate, various heart conditions, concomitant use of diuretics, and if you are a woman or over 65 years of age.
  • Grapefruit juice may increase the effect and should be avoided during treatment.
  • Can reinforce the influence of alcohol on consciousness and motor skills, which may, for example, be of significance in motor driving and operation of machines.
  • At the end of treatment, the dose should be reduced gradually (usually over at least 4 weeks). In case of sudden cessation, there is a risk of endometrial symptoms such as dizziness, shaking, nausea, insomnia and fatigue.

Using other medicines

It is important to inform your doctor about all the medicines you are taking.
  • Concomitant treatment with sumatriptan (migraine) or lithium (antidote) may lead to side effects.
  • Sertralin "Orion" should not be taken if you are taking pimozide (anticonvulsant), MAO inhibitors (anti-depressant, Parkinson's disease or infections) or if you have been treated with isocarboxazide within the last 14 days ( an MAO inhibitor).
  • Concomitant use of certain other anti-depressant agents (other SSRIs, SNRIs), certain painkillers (tramadol, fentanyl) and certain medicines for migraine (triptans) may cause serotonin syndrome (see section 4.8).
  • A number of other agents may increase or decrease the effect of Sertralin "Orion". This applies, inter alia, to certain medicines for infections, certain antifungal agents, certain medicines for HIV and certain heart medicines.
  • There is a risk of increased tendency to bleed if you also take medicines that may affect the blood's ability to clot (eg NSAIDs against pain).
  • Especially at high doses, sertraline may increase the effect of a variety of other means - including certain remedies for cardiac arrhythmia and certain other anti-depressant agents (tricyclic antidepressants).
  • If you also take warfarin (blood thinning), you may need to adjust the dose of warfarin.
  • Herbal preparations containing perikon may alter the effect of Sertralin "Orion".
  • Caution with concomitant use of agents that may lead to prolonged QT interval - a particular form of heart rhythm disturbances. This applies, inter alia, to certain remedies for heart rhythm disorders, certain antipsychotic drugs, and more antibiotics and antidepressants.

Grants, delivery, packages and prices

subsidiesextraditionDispensing form and strengthPackingPrice in kr.

Sertralin

May only be delivered once after the same prescription unless the recipient has stated on the prescription, how many times and with what time intervals additional extradition must take placefilm-coated tablets 50 mg100 pieces. (Blister)44,45

Sertralin

May only be delivered once after the same prescription unless the recipient has stated on the prescription, how many times and with what time intervals additional extradition must take placefilm-coated tablets100 mg100 pieces. (Blister)54,65


dyes

Titanium dioxide (E171)


substitution

film-coated tablets 50 mg

ZoloftPfizer Sertralin

Sertralin "Hexal" HEXAL Sertralin

Sertralin "KRKA" KRKA Sertralin

Sertralin "Teva" TEVA Sertralin

Sertralin "Accord" Accord Sertralin

film-coated tablets 100 mg

ZoloftPfizer Sertralin

Sertralin "Hexal" HEXAL Sertralin

Sertralin "KRKA" KRKA Sertralin

Sertralin "Teva" TEVA Sertralin



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